Effect of a single dose of 8 mg moxidectin or 150 μg/kg ivermectin on O. volvulus skin microfilariae in a randomized trial: Differences between areas in the Democratic Republic of the Congo, Liberia and Ghana and impact of intensity of infection.

Effect of a single dose of 8 mg moxidectin or 150 μg/kg ivermectin on O. volvulus skin microfilariae in a randomized trial: Differences between areas in the Democratic Republic of the Congo, Liberia and Ghana and impact of intensity of infection.

<h4>Background</h4>Our study in CDTI-naïve areas in Nord Kivu and Ituri (Democratic Republic of the Congo, DRC), Lofa County (Liberia) and Nkwanta district (Ghana) showed that a single 8 mg moxidectin dose reduced skin microfilariae density (microfilariae/mg skin, SmfD) better and for lo...

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Bibliographic Details
Main Authors: Didier Bakajika, Eric M Kanza, Nicholas O Opoku, Hayford M Howard, Germain L Mambandu, Amos Nyathirombo, Maurice M Nigo, Kambale Kasonia Kennedy, Safari L Masembe, Mupenzi Mumbere, Kambale Kataliko, Kpehe M Bolay, Simon K Attah, George Olipoh, Sampson Asare, Michel Vaillant, Christine M Halleux, Annette C Kuesel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0010079

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https://doi.org/10.1371/journal.pntd.0010079

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