Endogenous HMGB1 Modulates Fatty Acid Metabolism of Hypoxic and Nutrient-poor Pancreatic Cancer Cells and Related Mechanism

Endogenous HMGB1 Modulates Fatty Acid Metabolism of Hypoxic and Nutrient-poor Pancreatic Cancer Cells and Related Mechanism

Objective To explore the role and mechanism of HMGB1 in the fatty acid metabolism reprogramming and mitochondrial fusion/fission of hypoxic and nutrient-poor pancreatic cancer cells. Methods The correlation between the expression level of HMGB1 in pancreatic cancer tissue and the survival rate of pa...

Full description

Bibliographic Details
Main Authors: GAO Jie, WU Qiwei, SONG Lian, SHI Hui, WANG Ming, GONG Aihua, WANG Dongqing, ZHU Haitao
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2021-07-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
hypoxic/nutrient-poor
high-mobility group box-1
fatty acid de novo synthesis
mitochondrial fission/fusion
pancreatic cancer
Online Access:http://html.rhhz.net/ZLFZYJ/html/8578.2021.21.0038.htm

Internet

http://html.rhhz.net/ZLFZYJ/html/8578.2021.21.0038.htm

Similar Items