RACK1 facilitates breast cancer progression by competitively inhibiting the binding of β-catenin to PSMD2 and enhancing the stability of β-catenin

RACK1 facilitates breast cancer progression by competitively inhibiting the binding of β-catenin to PSMD2 and enhancing the stability of β-catenin

Abstract The receptor for activated C kinase 1 (RACK1) is a key scaffolding protein with multifunctional and multifaceted properties. By mediating protein-protein interactions, RACK1 integrates multiple intracellular signals involved in the regulation of various physiological and pathological proces...

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Bibliographic Details
Main Authors: Ruinan Tian, Jianfei Tian, Xiaoyan Zuo, Sixin Ren, He Zhang, Hui Liu, Zhiyong Wang, Yanfen Cui, Ruifang Niu, Fei Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06191-3

Internet

https://doi.org/10.1038/s41419-023-06191-3

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