Selective ligand recognition by a diversity-generating retroelement variable protein.

Diversity-generating retroelements (DGRs) recognize novel ligands through massive protein sequence variation, a property shared uniquely with the adaptive immune response. Little is known about how recognition is achieved by DGR variable proteins. Here, we present the structure of the Bordetella bac...

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Bibliographic Details
Main Authors: Jason L Miller, Johanne Le Coq, Asher Hodes, Roman Barbalat, Jeff F Miller, Partho Ghosh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-06-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2408619?pdf=render