Correlation of tumor mutational burden with prognosis and immune infiltration in lung adenocarcinoma

Correlation of tumor mutational burden with prognosis and immune infiltration in lung adenocarcinoma

BackgroundTumor mutational burden (TMB) plays an important role in the evaluation of immunotherapy efficacy in lung adenocarcinoma (LUAD).ObjectiveTo improve the clinical management of LUAD by investigating the prognostic value of TMB and the relationship between TMB and immune infiltration.MethodsT...

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Bibliographic Details
Main Authors: Lin Li, Junyu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Oncology
Subjects:
lung adenocarcinoma
tumor mutation burden
immune checkpoint blockade
the cancer genome atlas
cell proliferation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1128785/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1128785/full

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