Functional characterization of enhancer evolution in the primate lineage

Abstract Background Enhancers play an important role in morphological evolution and speciation by controlling the spatiotemporal expression of genes. Previous efforts to understand the evolution of enhancers in primates have typically studied many enhancers at low resolution, or single enhancers at...

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Bibliographic Details
Main Authors: Jason C. Klein, Aidan Keith, Vikram Agarwal, Timothy Durham, Jay Shendure
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-018-1473-6