RhoA within myofibers controls satellite cell microenvironment to allow hypertrophic growth

RhoA within myofibers controls satellite cell microenvironment to allow hypertrophic growth

Summary: Adult skeletal muscle is a plastic tissue that can adapt its size to workload. Here, we show that RhoA within myofibers is needed for overload-induced hypertrophy by controlling satellite cell (SC) fusion to the growing myofibers without affecting protein synthesis. At the molecular level,...

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Bibliographic Details
Main Authors: Chiara Noviello, Kassandra Kobon, Léa Delivry, Thomas Guilbert, Florian Britto, Francis Julienne, Pascal Maire, Voahangy Randrianarison-Huetz, Athanassia Sotiropoulos
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:iScience
Subjects:
Biological sciences
Cell biology
Stem cells research
Functional aspects of cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221015868

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http://www.sciencedirect.com/science/article/pii/S2589004221015868

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