Exploitation of tumor antigens and construction of immune subtype classifier for mRNA vaccine development in bladder cancer

Exploitation of tumor antigens and construction of immune subtype classifier for mRNA vaccine development in bladder cancer

BackgroundBladder cancer (BLCA) is one of the most prevalent urinary system malignancies, with high mortality and recurrence. The present study aimed to identify potential tumor antigens for mRNA vaccines in BLCA and patient subtypes suitable for different immunotherapy.MethodsGene expression profil...

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Bibliographic Details
Main Authors: Xin Zhang, Yanlong Zhang, Li Zhao, Jiayu Wang, Jiaxing Li, Xi Wang, Min Zhang, Xiaopeng Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
mRNA vaccine
tumor antigen
bladder cancer
immune subtypes
tumor immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1014638/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1014638/full

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