Isolation and Characterization of NpCI, a New Metallocarboxypeptidase Inhibitor from the Marine Snail <i>Nerita peloronta</i> with Anti-<i>Plasmodium falciparum</i> Activity

Isolation and Characterization of NpCI, a New Metallocarboxypeptidase Inhibitor from the Marine Snail <i>Nerita peloronta</i> with Anti-<i>Plasmodium falciparum</i> Activity

Metallocarboxypeptidases are zinc-dependent peptide-hydrolysing enzymes involved in several important physiological and pathological processes. They have been a target of growing interest in the search for natural or synthetic compound binders with biomedical and drug discovery purposes, i.e., with...

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Bibliographic Details
Main Authors: Aymara Cabrera-Muñoz, Yusvel Sierra-Gómez, Giovanni Covaleda-Cortés, Mey L. Reytor, Yamile González-González, José M. Bautista, Francesc Xavier Avilés, Maday Alonso-del-Rivero
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Marine Drugs
Subjects:
metallocarboxipeptidases
carboxypeptidase inhibitor
slow- and tight-binding inhibitor
marine invertebrate
<i>Plasmodium falciparum</i>
antimalarial
Online Access:https://www.mdpi.com/1660-3397/21/2/94

Internet

https://www.mdpi.com/1660-3397/21/2/94

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