Effect of synaptic transmission on viral fitness in HIV infection.

HIV can spread through its target cell population either via cell-free transmission, or by cell-to-cell transmission, presumably through virological synapses. Synaptic transmission entails the transfer of tens to hundreds of viruses per synapse, a fraction of which successfully integrate into the ta...

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Bibliographic Details
Main Authors: Natalia L Komarova, David N Levy, Dominik Wodarz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3499495?pdf=render