Thymic versus induced regulatory T cells – who regulates the regulators?

Physiological health must balance immunological responsiveness against foreign pathogens with tolerance towards self-components and commensals. Disruption of this balance causes autoimmune diseases/chronic inflammation, in case of excessive immune responses, and persistent infection/immunodeficiency...

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Bibliographic Details
Main Authors: Giovanni Antonio Maria Povoleri, Cristiano eScotta, Estefania Andrea Nova-Lamperti, Susan eJohn, Giovanna eLombardi, Behdad eAfzali
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00169/full