How Scaffolds shape MAPK signalling: What we know and opportunities for systems approaches

Scaffolding proteins add a new layer of complexity to the dynamics of cell signalling. Above their basic function to bring several components of a signalling pathway together, recent experimental research has found that scaffolds influence signalling in a much more complex way: Scaffolds can exert s...

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Bibliographic Details
Main Authors: Franziska eWitzel, Louise E. Maddison, Nils eBlüthgen
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-12-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00475/full