Changes in Left Ventricular Ejection Fraction and Oxidative Stress after Phosphodiesterase Type-5 Inhibitor Treatment in an Experimental Model of Retrograde Rat Perfusion

Changes in Left Ventricular Ejection Fraction and Oxidative Stress after Phosphodiesterase Type-5 Inhibitor Treatment in an Experimental Model of Retrograde Rat Perfusion

<i>Background and objectives</i>: Taking into consideration the confirmed role of oxidative stress in ischemia/reperfusion injury and the insufficiency in knowledge regarding the phosphodiesterase 5 (PDE5)-mediated effects on the cardiovascular system, the aim of our study was to investi...

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Bibliographic Details
Main Authors: Milos Krivokapic, Israpil Alisultanovich Omarov, Vladimir Zivkovic, Tamara Nikolic Turnic, Vladimir Jakovljevic
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Medicina
Subjects:
tadalafil
vardenafil
oxidative stress
ejection fractioning
isolated rat heart
Langendorff technique
Online Access:https://www.mdpi.com/1648-9144/59/3/458

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https://www.mdpi.com/1648-9144/59/3/458

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