Exploring heterogeneity of tumor immune cells and adrenal cells in aldosterone-producing adenomas using single-cell RNA-seq and investigating differences by sex

Exploring heterogeneity of tumor immune cells and adrenal cells in aldosterone-producing adenomas using single-cell RNA-seq and investigating differences by sex

The mechanism behind the higher incidence of aldosterone-producing adenoma (APA) in women compared to men is not yet understood. In this study, we utilized single-cell RNA sequencing (scRNA-seq) to investigate the immune cell infiltration and adrenal cell characteristics in APA. Our findings reveale...

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Bibliographic Details
Main Authors: Jing Huang, Fei Qin, Xiaomei Lai, Tingting Yang, Jie Yu, Chaoping Wei, Lixia Wei, Jianling Li
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Heliyon
Subjects:
Aldosterone-producing adenoma
Single-cell RNA sequencing
Tumor microenvironment
Gender
Immune cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023015645

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http://www.sciencedirect.com/science/article/pii/S2405844023015645

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