Distinct clinical pattern of colorectal cancer patients with POLE mutations: A retrospective study on real-world data

Objective: Studies have demonstrated an association between somatic POLE exonuclease domain mutations (EDMs) and the prognosis of colorectal cancer (CRC). However, the prognostic value of POLE non-EDMs remains unclear. This retrospective study aimed to explore the possible relationships between POLE...

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Bibliographic Details
Main Authors: Miao Jiang, Yongliang Jia, Jinming Han, Jianxiang Shi, Chang Su, Rui Zhang, Menglu Xing, Shuiling Jin, Hong Zong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.963964/full