Evaluating the association of TRPA1 gene polymorphisms with pain sensitivity: a protocol for an adaptive recall by genotype study

Evaluating the association of TRPA1 gene polymorphisms with pain sensitivity: a protocol for an adaptive recall by genotype study

Abstract Background Pain is a complex polygenic trait whose common genetic underpinnings are relatively ill-defined due in part to challenges in measuring pain as a phenotype. Pain sensitivity can be quantified, but this is difficult to perform at the scale required for genome wide association studi...

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Bibliographic Details
Main Authors: Aidan P. Nickerson, Laura J. Corbin, Nicholas J. Timpson, Keith Phillips, Anthony E. Pickering, James P. Dunham
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Medical Genomics
Subjects:
ALSPAC
Recall by genotype
Adaptive design
Pain
Quantitative sensory testing
TRPA1
Online Access:https://doi.org/10.1186/s12920-022-01156-5

Internet

https://doi.org/10.1186/s12920-022-01156-5

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