Unc13A dynamically stabilizes vesicle priming at synaptic release sites for short-term facilitation and homeostatic potentiation

Unc13A dynamically stabilizes vesicle priming at synaptic release sites for short-term facilitation and homeostatic potentiation

Summary: Presynaptic plasticity adjusts neurotransmitter (NT) liberation. Short-term facilitation (STF) tunes synapses to millisecond repetitive activation, while presynaptic homeostatic potentiation (PHP) of NT release stabilizes transmission over minutes. Despite different timescales of STF and PH...

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Bibliographic Details
Main Authors: Meida Jusyte, Natalie Blaum, Mathias A. Böhme, Manon M.M. Berns, Alix E. Bonard, Ábel B. Vámosi, Kavya V. Pushpalatha, Janus R.L. Kobbersmed, Alexander M. Walter
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723005521

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http://www.sciencedirect.com/science/article/pii/S2211124723005521

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