Potential Chemopreventive Activity of a New Macrolide Antibiotic from a Marine-Derived Micromonospora sp.

Agents capable of inducing phase II enzymes such as quinone reductase 1 (QR1) are known to have the potential of mediating cancer chemopreventive activity. As part of a program to discover novel phase II enzyme-inducing molecules, we identified a marine-derived actinomycete strain (CNJ-878) that exh...

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Bibliographic Details
Main Authors: Brian T. Murphy, John M. Pezzuto, Sang-Jip Nam, Bernard D. Santarsiero, Laura Marler, Skylar Carlson
Format: Article
Language:English
Published: MDPI AG 2013-04-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/11/4/1152