Selecting antibacterial aptamers against the BamA protein in Pseudomonas aeruginosa by incorporating genetic algorithm to optimise computational screening method

Abstract Antibiotic resistance is one of the biggest threats to global health resulting in an increasing number of people suffering from severe illnesses or dying due to infections that were once easily curable with antibiotics. Pseudomonas aeruginosa is a major pathogen that has rapidly developed a...

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Bibliographic Details
Main Authors: Rupany Selvam, Ian Han Yan Lim, Jovita Catherine Lewis, Chern Hong Lim, Michelle Khai Khun Yap, Hock Siew Tan
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-34643-5