Cholesterol absorption blocker ezetimibe prevents muscle wasting in severe dysferlin‐deficient and mdx mice
Abstract Background Muscular dystrophy (MD) causes muscle wasting and is often lethal in patients due to a lack of proven therapies. In contrast, mouse models of MD are notoriously mild. We have previously shown severe human‐like muscle pathology in mdx [Duchenne MD (DMD)] and dysferlin‐deficient li...
Κύριοι συγγραφείς: | , , , , , , , |
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Μορφή: | Άρθρο |
Γλώσσα: | English |
Έκδοση: |
Wiley
2022-02-01
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Σειρά: | Journal of Cachexia, Sarcopenia and Muscle |
Θέματα: | |
Διαθέσιμο Online: | https://doi.org/10.1002/jcsm.12879 |