Cholesterol absorption blocker ezetimibe prevents muscle wasting in severe dysferlin‐deficient and mdx mice

Abstract Background Muscular dystrophy (MD) causes muscle wasting and is often lethal in patients due to a lack of proven therapies. In contrast, mouse models of MD are notoriously mild. We have previously shown severe human‐like muscle pathology in mdx [Duchenne MD (DMD)] and dysferlin‐deficient li...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Zoe White, Marine Theret, Nadia Milad, Lin Wei Tung, William Wei‐Han Chen, Martin G. Sirois, Fabio Rossi, Pascal Bernatchez
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Wiley 2022-02-01
Σειρά:Journal of Cachexia, Sarcopenia and Muscle
Θέματα:
Διαθέσιμο Online:https://doi.org/10.1002/jcsm.12879