BH4 supplementation reduces retinal cell death in ischaemic retinopathy

Abstract Dysregulation of nitric oxide (NO) production can cause ischaemic retinal injury and result in blindness. How this dysregulation occurs is poorly understood but thought to be due to an impairment in NO synthase function (NOS) and nitro-oxidative stress. Here we investigated the possibility...

Full description

Bibliographic Details
Main Authors: Kevin S. Edgar, Ciara Cunning, Tom A. Gardiner, Denise M. McDonald
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48167-5