Structure/Function Analysis of human ZnT8 (SLC30A8): A Diabetes Risk Factor and Zinc Transporter
The human zinc transporter ZnT8 (SLC30A8) is expressed primarily in pancreatic β-cells and plays a key function in maintaining the concentration of blood glucose through its role in insulin storage, maturation and secretion. ZnT8 is an autoantigen for Type 1 diabetes (T1D) and is associated with Typ...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
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Series: | Current Research in Structural Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2665928X2030012X |