Hepatic regulator of G protein signaling 14 ameliorates NAFLD through activating cAMP-AMPK signaling by targeting Giα1/3

Hepatic regulator of G protein signaling 14 ameliorates NAFLD through activating cAMP-AMPK signaling by targeting Giα1/3

Objective: Nonalcoholic fatty liver disease (NAFLD) is an emerging public health threat as the most common chronic liver disease worldwide. However, there remains no effective medication to improve NAFLD. G protein-coupled receptors (GPCRs) are the most frequently investigated drug targets family. T...

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Bibliographic Details
Main Authors: Junyong Wang, Yaping Guo, Yunduan He, Yifan Qin, Xiuling Li, Ling Yang, Kangdong Liu, Li Xiao
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Molecular Metabolism
Subjects:
Lipotoxicity
Lipid accumulation
Inflammation
Steatosis
GDI
GPCR
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877824000139

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http://www.sciencedirect.com/science/article/pii/S2212877824000139

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