NAD+ metabolism controls inflammation during senescence

NAD+ metabolism controls inflammation during senescence

We have recently discovered that nicotinamide adenine dinucleotide metabolism controls the pro-inflammatory senescence-associated secretory phenotype during cellular senescence. This newly discovered epigenetic-metabolic signaling axis, mediated by high mobility group A and nicotinamide phosphoribos...

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Bibliographic Details
Main Authors: Timothy Nacarelli, Rugang Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2019-07-01
Series:Molecular & Cellular Oncology
Subjects:
cellular senescence
senescence-associated secretory phenotype (sasp)
nad+
nampt
hmga
Online Access:http://dx.doi.org/10.1080/23723556.2019.1605819

Internet

http://dx.doi.org/10.1080/23723556.2019.1605819

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