α-Hemolysin promotes uropathogenic E. coli persistence in bladder epithelial cells via abrogating bacteria-harboring lysosome acidification.

α-Hemolysin promotes uropathogenic E. coli persistence in bladder epithelial cells via abrogating bacteria-harboring lysosome acidification.

There is a growing consensus that a significant proportion of recurrent urinary tract infections are linked to the persistence of uropathogens within the urinary tract and their re-emergence upon the conclusion of antibiotic treatment. Studies in mice and human have revealed that uropathogenic Esche...

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Bibliographic Details
Main Authors: Manisha Naskar, Viraj P Parekh, Mathew A Abraham, Zehra Alibasic, Min Jung Kim, Gyeongseo Suk, Joo Hwan Noh, Kwan Young Ko, Joonha Lee, Chungho Kim, Hana Yoon, Soman N Abraham, Hae Woong Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011388

Internet

https://doi.org/10.1371/journal.ppat.1011388

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