In vitro and in vivo effects of digoxin derivatives on promastigotes and amastigotes of Leishmania infantum

In vitro and in vivo effects of digoxin derivatives on promastigotes and amastigotes of Leishmania infantum

Leishmania infantum is responsible for visceral leishmaniasis, the most severe form of the disease. The treatments currently used are pentavalent antimonials and amphotericin B, but they present serious side effects and resistant species that already exist. Therefore, it is necessary to find new com...

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Bibliographic Details
Main Authors: Gabriellen Menezes Migliani de Castro, Yasmin da Silva Fontes, Silmara Lúcia Grego Alves, Leandro Augusto Oliveira Barbosa, José Augusto Ferreira Perez Villar, Antonio Galina Filho, Sergio Henrique Seabra, Anna Lea Silva Barreto, Ana Claudia Tessis, Dirlei Nico, Antonio Ferreira-Pereira
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Journal of Taibah University for Science
Subjects:
Leishmania
L. infantum
leishmaniasis
digoxin
digitalis
Online Access:https://www.tandfonline.com/doi/10.1080/16583655.2023.2289240

Internet

https://www.tandfonline.com/doi/10.1080/16583655.2023.2289240

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