Computational approaches for discovering significant microRNAs, microRNA-mRNA regulatory pathways, and therapeutic protein targets in endometrial cancer

Computational approaches for discovering significant microRNAs, microRNA-mRNA regulatory pathways, and therapeutic protein targets in endometrial cancer

Endometrial cancer (EC) is a urogenital cancer affecting millions of post-menopausal women, globally. This study aims to identify key miRNAs, target genes, and drug targets associated with EC metastasis. The global miRNA and mRNA expression datasets of endometrial tissue biopsies (24 tumors +3 healt...

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Bibliographic Details
Main Authors: Ghada Ajabnoor, Fai Alsubhi, Thoraia Shinawi, Wisam Habhab, Walaa F. Albaqami, Hussain S. Alqahtani, Hisham Nasief, Nabeel Bondagji, Ramu Elango, Noor Ahmad Shaik, Babajan Banaganapalli
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Genetics
Subjects:
endometrial cancer
microRNA
gene expression
PPI
cancer drug targets
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1105173/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.1105173/full

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