Mining and characterization of the PKS–NRPS hybrid for epicoccamide A: a mannosylated tetramate derivative from Epicoccum sp. CPCC 400996

Mining and characterization of the PKS–NRPS hybrid for epicoccamide A: a mannosylated tetramate derivative from Epicoccum sp. CPCC 400996

Abstract Background Genomic analysis indicated that the genomes of ascomycetes might carry dozens of biosynthetic gene clusters (BGCs), yet many clusters have remained enigmatic. The ascomycete genus Epicoccum, belonging to the family Didymellaceae, is ubiquitous that colonizes different types of su...

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Bibliographic Details
Main Authors: Tao Zhang, Guowei Cai, Xiaoting Rong, Jingwen Xu, Bingya Jiang, Hao Wang, Xinxin Li, Lu Wang, Ran Zhang, Wenni He, Liyan Yu
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Microbial Cell Factories
Subjects:
Epicoccamide
Genome mining
PKS−NRPS hybrid
Tetramates
Biosynthesis
Epicoccum
Online Access:https://doi.org/10.1186/s12934-022-01975-2

Internet

https://doi.org/10.1186/s12934-022-01975-2

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