Key considerations for comprehensive validation of an RNA fusion NGS panel

Key considerations for comprehensive validation of an RNA fusion NGS panel

Objectives: Validation of RNA-based NGS assays for the detection of therapeutically targetable gene fusions is challenging. Here, we report systematic validation and quality control monitoring of our targeted fusion panel for the detection of 17 clinically relevant fusion transcripts across several...

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Bibliographic Details
Main Authors: Subit Barua, Gary Wang, Mahesh Mansukhani, Susan Hsiao, Helen Fernandes
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Practical Laboratory Medicine
Subjects:
Next generation sequencing
Precision medicine
Molecular oncology
Assay
Validation
RNA Fusions
Online Access:http://www.sciencedirect.com/science/article/pii/S2352551719301313

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http://www.sciencedirect.com/science/article/pii/S2352551719301313

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