Exosomal miR-3174 induced by hypoxia promotes angiogenesis and metastasis of hepatocellular carcinoma by inhibiting HIPK3

Summary: Hepatocellular carcinoma (HCC) is a highly malignant tumor with rich blood supply. HCC-derived exosomes containing hereditary substances including microRNAs (miRNAs) were involved in regulating tumor angiogenesis and metastasis. Subsequently, series experiments were performed to evaluate th...

Full description

Bibliographic Details
Main Authors: Xiao Yang, Mingyu Wu, Xiangxu Kong, Yun Wang, Chunyang Hu, Deming Zhu, Lianbao Kong, Fei Qiu, Wangjie Jiang
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224001767