Plastic and behavioral abnormalities in experimental Huntington's disease: A crucial role for cholinergic interneurons

Plastic and behavioral abnormalities in experimental Huntington's disease: A crucial role for cholinergic interneurons

Huntington's disease (HD) is a fatal hereditary neurodegenerative disease causing degeneration of striatal spiny neurons, whereas cholinergic interneurons are spared. This cell-type specific pathology produces an array of abnormalities including involuntary movements, cognitive impairments, and...

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Bibliographic Details
Main Authors: Barbara Picconi, Enrica Passino, Carmelo Sgobio, Paola Bonsi, Ilaria Barone, Veronica Ghiglieri, Antonio Pisani, Giorgio Bernardi, Martine Ammassari-Teule, Paolo Calabresi
Format: Article
Language:English
Published: Elsevier 2006-04-01
Series:Neurobiology of Disease
Subjects:
Huntington's disease
HD animal models
Synaptic plasticity
Striatum
Plastic abnormalities
3-Nitropropionic acid
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105002809

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http://www.sciencedirect.com/science/article/pii/S0969996105002809

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