Gamma-irradiated influenza A virus provides adjuvant activity to a co-administered poorly immunogenic SFV vaccine in mice.

Gamma-irradiated influenza A virus provides adjuvant activity to a co-administered poorly immunogenic SFV vaccine in mice.

Many currently available inactivated vaccines require 'adjuvants' to maximise the protective immune responses generated against the antigens of interest. Recent studies in mice with gamma-irradiated influenza A virus (γ-FLU) have shown its superior efficacy compared to other forms of inact...

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Bibliographic Details
Main Authors: Rachelle eBabb, Jennifer eChan, Jasmine E Khairat, Yoichi eFuruya, Mohammed eAlsharifi
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Immunology
Subjects:
Antibodies
Influenza Vaccines
adjuvants
combined vaccine
gamma-irradiation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00267/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00267/full

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