The Effects of Peripubertal THC Exposure in Neurodevelopmental Rat Models of Psychopathology

The Effects of Peripubertal THC Exposure in Neurodevelopmental Rat Models of Psychopathology

Adolescent exposure to cannabinoids as a postnatal environmental insult may increase the risk of psychosis in subjects exposed to perinatal insult, as suggested by the two-hit hypothesis of schizophrenia. Here, we hypothesized that peripubertal Δ<sup>9</sup>-tetrahydrocannabinol (aTHC) m...

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Bibliographic Details
Main Authors: Martina Di Bartolomeo, Tibor Stark, Serena Di Martino, Fabio Arturo Iannotti, Jana Ruda-Kucerova, Giovanni Luca Romano, Martin Kuchar, Samuele Laudani, Petr Palivec, Fabiana Piscitelli, Carsten T. Wotjak, Claudio Bucolo, Filippo Drago, Vincenzo Di Marzo, Claudio D’Addario, Vincenzo Micale
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
Δ<sup>9</sup>-tetrahydrocannabinol
methylazoxymethanol acetate
dopamine D2/D3 receptors
psychopathology
Online Access:https://www.mdpi.com/1422-0067/24/4/3907

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https://www.mdpi.com/1422-0067/24/4/3907

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