Fluorofenidone inhibits apoptosis of renal tubular epithelial cells in rats with renal interstitial fibrosis

Fluorofenidone inhibits apoptosis of renal tubular epithelial cells in rats with renal interstitial fibrosis

This study aimed to investigate the mechanism of fluorofenidone (AKF-PD) in treating renal interstitial fibrosis in rats with unilateral urinary obstruction (UUO). Thirty-two male Sprague-Dawley rats were randomly divided into sham, UUO, UUO + enalapril, and UUO + AKF-PD groups. All rats, except sha...

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Bibliographic Details
Main Authors: Hui Yang, Weiru Zhang, Tingting Xie, Xuan Wang, Wangbin Ning
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2019-10-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Fluorofenidone
Unilateral ureteral obstruction
Renal fibrosis
Apoptosis
Enalapril
Online Access:http://www.scielo.br/pdf/bjmbr/v52n11/1414-431X-bjmbr-52-11-e8772.pdf

Internet

http://www.scielo.br/pdf/bjmbr/v52n11/1414-431X-bjmbr-52-11-e8772.pdf

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