Bio-integrated scaffold facilitates large bone regeneration dominated by endochondral ossification

Bio-integrated scaffold facilitates large bone regeneration dominated by endochondral ossification

Repair of large bone defects caused by severe trauma, non-union fractures, or tumor resection remains challenging because of limited regenerative ability. Typically, these defects heal through mixed routines, including intramembranous ossification (IMO) and endochondral ossification (ECO), with ECO...

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Bibliographic Details
Main Authors: Lili Sun, Haoyi Niu, Yuqiong Wu, Shiyan Dong, Xuefeng Li, Betty Y.S. Kim, Changsheng Liu, Yifan Ma, Wen Jiang, Yuan Yuan
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-05-01
Series:Bioactive Materials
Subjects:
Endochondral ossification
Bio-integrated scaffold
Hypoxia-mimicking
Low-dose bone morphogenetic protein-2
Large bone repair
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2400029X

Internet

http://www.sciencedirect.com/science/article/pii/S2452199X2400029X

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