Bio-integrated scaffold facilitates large bone regeneration dominated by endochondral ossification

Bio-integrated scaffold facilitates large bone regeneration dominated by endochondral ossification

Repair of large bone defects caused by severe trauma, non-union fractures, or tumor resection remains challenging because of limited regenerative ability. Typically, these defects heal through mixed routines, including intramembranous ossification (IMO) and endochondral ossification (ECO), with ECO...

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Bibliographic Details
Main Authors:	Lili Sun, Haoyi Niu, Yuqiong Wu, Shiyan Dong, Xuefeng Li, Betty Y.S. Kim, Changsheng Liu, Yifan Ma, Wen Jiang, Yuan Yuan
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2024-05-01
Series:	Bioactive Materials
Subjects:	Endochondral ossification Bio-integrated scaffold Hypoxia-mimicking Low-dose bone morphogenetic protein-2 Large bone repair
Online Access:	http://www.sciencedirect.com/science/article/pii/S2452199X2400029X

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