High-sensitivity HLA typing by Saturated Tiling Capture Sequencing (STC-Seq)

High-sensitivity HLA typing by Saturated Tiling Capture Sequencing (STC-Seq)

Abstract Background Highly polymorphic human leukocyte antigen (HLA) genes are responsible for fine-tuning the adaptive immune system. High-resolution HLA typing is important for the treatment of autoimmune and infectious diseases. Additionally, it is routinely performed for identifying matched dono...

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Bibliographic Details
Main Authors: Yang Jiao, Ran Li, Chao Wu, Yibin Ding, Yanning Liu, Danmei Jia, Lifeng Wang, Xiang Xu, Jing Zhu, Min Zheng, Junling Jia
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Genomics
Subjects:
Human leukocyte antigen (HLA)
Hybridization capture
HLA typing
Next-generation sequencing (NGS)
Third-generation sequencing
Online Access:http://link.springer.com/article/10.1186/s12864-018-4431-5

Internet

http://link.springer.com/article/10.1186/s12864-018-4431-5

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