VDR Regulates BNP Promoting Neurite Growth and Survival of Cochlear Spiral Ganglion Neurons through cGMP-PKG Signaling Pathway

VDR Regulates BNP Promoting Neurite Growth and Survival of Cochlear Spiral Ganglion Neurons through cGMP-PKG Signaling Pathway

Spiral ganglion neurons (SGNs) are important for hearing, and their peripheral and central processes connect sensory cells of the Corti organ to the central nervous system. The resulting network forms a point-to-point auditory conduction. As a cardiac hormone, brain natriuretic peptide (BNP) binds t...

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Bibliographic Details
Main Authors: Xinyu Zhang, Ke Zhou, Keyong Tian, Qingwen Zhu, Wei Liu, Zhenzhen Liu, Xiaogang An, Chaoyong Tian, Yao Li, Fei Lu, Fei Sun, Dingjun Zha
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
sensorineural hearing loss
vitamin D receptor
brain natriuretic peptide
spiral ganglion neurons
neuronal regeneration therapy
Online Access:https://www.mdpi.com/2073-4409/11/23/3746

Internet

https://www.mdpi.com/2073-4409/11/23/3746

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