Toll-like receptor 2 expression on c-kit+ cells tracks the emergence of embryonic definitive hematopoietic progenitors

Toll-like receptor 2 expression on c-kit+ cells tracks the emergence of embryonic definitive hematopoietic progenitors

There is limited knowledge of markers to identify various waves of murine embryonic hematopoiesis. Here, the authors show that the expression of toll-like receptor 2 (TLR2) on E7.5 c-kit+ cells marks the emergence of erythro-myeloid progenitor precursors and that the Tlr2 locus is active in E8.5 pre...

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Bibliographic Details
Main Authors: Jana Balounová, Iva Šplíchalová, Martina Dobešová, Michal Kolář, Karel Fišer, Jan Procházka, Radislav Sedlacek, Andrea Jurisicova, Hoon-ki Sung, Vladimír Kořínek, Meritxell Alberich-Jorda, Isabelle Godin, Dominik Filipp
Format: Article
Language:English
Published: Nature Portfolio 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13150-0

Internet

https://doi.org/10.1038/s41467-019-13150-0

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