The Role of Necroptosis: Biological Relevance and Its Involvement in Cancer

The Role of Necroptosis: Biological Relevance and Its Involvement in Cancer

Regulated cell death mechanisms are essential for the maintenance of cellular homeostasis. Evasion of cell death is one of the most important hallmarks of cancer. Necroptosis is a caspase independent form of regulated cell death, investigated as a novel therapeutic strategy to eradicate apoptosis re...

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Bibliographic Details
Main Authors: Laura Della Torre, Angela Nebbioso, Hendrik G. Stunnenberg, Joost H. A. Martens, Vincenzo Carafa, Lucia Altucci
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
necroptosis
cancer
RIPK1
RIPK1 mutations
Online Access:https://www.mdpi.com/2072-6694/13/4/684

Internet

https://www.mdpi.com/2072-6694/13/4/684

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