Multi-Level Analysis and Identification of Tumor Mutational Burden Genes across Cancer Types

Multi-Level Analysis and Identification of Tumor Mutational Burden Genes across Cancer Types

Tumor mutational burden (TMB) is considered a potential biomarker for predicting the response and effect of immune checkpoint inhibitors (ICIs). However, there are still inconsistent standards of gene panels using next-generation sequencing and poor correlation between the TMB genes, immune cell inf...

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Bibliographic Details
Main Authors: Shuangkuai Wang, Yuantao Tong, Hui Zong, Xuewen Xu, M. James C. Crabbe, Ying Wang, Xiaoyan Zhang
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Genes
Subjects:
tumor mutational burden
next-generation sequencing gene panel
omics data mining
tumor-infiltrating lymphocytes
Online Access:https://www.mdpi.com/2073-4425/13/2/365

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https://www.mdpi.com/2073-4425/13/2/365

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