Functionalization of Silica Nanoparticles for Tailored Interactions with Intestinal Cells and Chemical Modulation of Paracellular Permeability

Functionalization of Silica Nanoparticles for Tailored Interactions with Intestinal Cells and Chemical Modulation of Paracellular Permeability

The intestinal compartment confines the gut microbiome while enabling food passage and absorption of active molecules. For the rational design of oral formulations aiming to overcome physiological barriers of the gut, it is crucial to understand how cells respond to the presence of nanoparticulate m...

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Bibliographic Details
Main Authors: Claudia Iriarte‐Mesa, Janice Bergen, Kristina Danielyan, Francesco Crudo, Doris Marko, Hanspeter Kählig, Giorgia Del Favero, Freddy Kleitz
Format: Article
Language:English
Published: Wiley-VCH 2025-01-01
Series:Small Science
Subjects:
differentiated intestinal cells
membrane permeation
mesoporous silica nanoparticles
mucus barrier
surface functions
tight junction proteins
Online Access:https://doi.org/10.1002/smsc.202400112

Internet

https://doi.org/10.1002/smsc.202400112

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