Evolutionary conservation of DNA methylation in CpG sites within ultraconserved noncoding elements

Evolutionary conservation of DNA methylation in CpG sites within ultraconserved noncoding elements

Ultraconserved noncoding elements (UCNEs) constitute less than 1 Mb of vertebrate genomes and are impervious to accumulating mutations. About 4000 UCNEs exist in vertebrate genomes, each at least 200 nucleotides in length, sharing greater than 95% sequence identity between human and chicken. Despite...

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Bibliographic Details
Main Authors: Mathia Colwell, Melissa Drown, Kelly Showel, Chelsea Drown, Amanda Palowski, Christopher Faulk
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Epigenetics
Subjects:
epigenetics
dna methylation
phylogenetic least squares
cpg density
evolution
varmints
ultraconserved noncoding elements
Online Access:http://dx.doi.org/10.1080/15592294.2017.1411447

Internet

http://dx.doi.org/10.1080/15592294.2017.1411447

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