Progress in construction of hypoxia-sensitive CAR-T cell for solid tumor therapy

Chimeric antigen receptor T (CAR-T) cell therapy, as a kind of tumor immunotherapy, has made remarkable achievements for the treatment of hematological malignancy. Disappointingly, regarding solid tumors, CAR-T cells generally target tumor-associated antigens that are also widely expressed in normal...

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Bibliographic Details
Main Author: XUE Ying, MAO Yunyu, XU Jianqing
Format: Article
Language:English
Published: Editorial Office of China Oncology 2023-01-01
Series:Zhongguo aizheng zazhi
Subjects:
Online Access:http://www.china-oncology.com/fileup/1007-3639/PDF/1676258293239-942499708.pdf