Resistivity Technique for the Evaluation of the Integrity of Buccal and Esophageal Epithelium Mucosa for In Vitro Permeation Studies: Swine Buccal and Esophageal Mucosa Barrier Models

Resistivity Technique for the Evaluation of the Integrity of Buccal and Esophageal Epithelium Mucosa for In Vitro Permeation Studies: Swine Buccal and Esophageal Mucosa Barrier Models

Permeation assays are important for the development of topical formulations applied on buccal mucosa. Swine buccal and esophageal epithelia are usually used as barriers for these assays, while frozen epithelia have been used to optimize the experimental setup. However, there is no consensus on these...

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Bibliographic Details
Main Authors: Jaiza Samara Macena de Araújo, Maria Cristina Volpato, Bruno Vilela Muniz, Gabriela Gama Augusto Xavier, Claudia Cristina Maia Martinelli, Renata Fonseca Vianna Lopez, Francisco Carlos Groppo, Michelle Franz-Montan
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pharmaceutics
Subjects:
membrane resistivity
esophageal epithelium
buccal epithelium
mucosal drug delivery
in vitro models
transbuccal drug delivery
Online Access:https://www.mdpi.com/1999-4923/13/5/643

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https://www.mdpi.com/1999-4923/13/5/643

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