Intermolecular 2+2 imine-olefin photocycloadditions enabled by Cu(I)-alkene MLCT

An ideal method to construct azetidines would be through a [2 + 2] photocycloaddition that joins an olefin and an imine, shown only rarely in the literature, partially due to competitive photochemical processes of the imine. Here, the authors report copper-catalyzed photocycloadditions of imines and...

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Bibliographic Details
Main Authors: Daniel M. Flores, Michael L. Neville, Valerie A. Schmidt
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30393-6