Astaxanthin attenuates cigarette smoke-induced small airway remodeling via the AKT1 signaling pathway

Abstract Background Astaxanthin (AXT) is a keto-carotenoid with a variety of biological functions, including antioxidant and antifibrotic effects. Small airway remodeling is the main pathology of chronic obstructive pulmonary disease (COPD) and is caused by epithelial-to-mesenchymal transition (EMT)...

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Bibliographic Details
Main Authors: Haidong Ding, Liming Yan, Yu Wang, Ye Lu, Mingming Deng, Yingxi Wang, Qiuyue Wang, Xiaoming Zhou
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-024-02768-4