Sequestration within peptide coacervates improves the fluorescence intensity, kinetics, and limits of detection of dye-based DNA biosensors
Abstract Peptide-based liquid-liquid phase separated domains, or coacervates, are a biomaterial gaining new interest due to their exciting potential in fields ranging from biosensing to drug delivery. In this study, we demonstrate that coacervates provide a simple and biocompatible medium to improve...
Main Authors: | Christopher M. Green, Deborah Sementa, Divita Mathur, Joseph S. Melinger, Priyasha Deshpande, Shana Elbaum-Garfinkle, Igor L. Medintz, Rein V. Ulijn, Sebastián A. Díaz |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-02-01
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Series: | Communications Chemistry |
Online Access: | https://doi.org/10.1038/s42004-024-01124-3 |
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