Ion elemental-optimized layered double hydroxide nanoparticles promote chondrogenic differentiation and intervertebral disc regeneration of mesenchymal stem cells through focal adhesion signaling pathway

Ion elemental-optimized layered double hydroxide nanoparticles promote chondrogenic differentiation and intervertebral disc regeneration of mesenchymal stem cells through focal adhesion signaling pathway

Chronic low back pain and dyskinesia caused by intervertebral disc degeneration (IDD) are seriously aggravated and become more prevalent with age. Current clinical treatments do not restore the biological structure and inherent function of the disc. The emergence of tissue engineering and regenerati...

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Bibliographic Details
Main Authors: Zhaojie Wang, Huiyi Yang, Xu Xu, Hongxing Hu, Yuxin Bai, Jian Hai, Liming Cheng, Rongrong Zhu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-04-01
Series:Bioactive Materials
Subjects:
Mesenchymal stem cells
Layered double hydroxide
Chondrogenic differentiation
Intervertebral disc degeneration
Focal adhesion signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X22003668

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http://www.sciencedirect.com/science/article/pii/S2452199X22003668

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