Systematic review of computational methods for drug combination prediction

Systematic review of computational methods for drug combination prediction

Synergistic effects between drugs are rare and highly context-dependent and patient-specific. Hence, there is a need to develop novel approaches to stratify patients for optimal therapy regimens, especially in the context of personalized design of combinatorial treatments. Computational methods enab...

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Bibliographic Details
Main Authors: Weikaixin Kong, Gianmarco Midena, Yingjia Chen, Paschalis Athanasiadis, Tianduanyi Wang, Juho Rousu, Liye He, Tero Aittokallio
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Drug combinations
Synergistic effect
Selective effect
Literature review
Dose–response assay
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022002100

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http://www.sciencedirect.com/science/article/pii/S2001037022002100

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